Microfluidics-Based Enrichment and Whole-Genome Amplification Enable Strain-Level Resolution for Airway Metagenomics

Microfluidics-Based Enrichment and Whole-Genome Amplification Enable Strain-Level Resolution for Airway Metagenomics

ABSTRACT Dysbiosis of airway microbiomes has been found in various respiratory diseases, but its molecular details in terms of taxonomic profile, metabolic characteristics, defensive function, and inhabit adaption are far from clear. Shotgun metagenome sequencing provides detailed information for mi...

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Bibliographic Details
Main Authors: Xing Shi, Changjun Shao, Chunxiong Luo, Yanan Chu, Jian Wang, Qingren Meng, Jun Yu, Zhancheng Gao, Yu Kang
Format: Article
Language:English
Published: American Society for Microbiology 2019-08-01
Series:mSystems
Subjects:
emulsion
metagenomics
microfluidic chip
respiratory microbiome
Online Access:https://journals.asm.org/doi/10.1128/mSystems.00198-19

Internet

https://journals.asm.org/doi/10.1128/mSystems.00198-19

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