Integrin β5 subunit regulates hyperglycemia-induced vascular endothelial cell apoptosis through FoxO1-mediated macroautophagy

Abstract. Background:. Hyperglycemia frequently induces apoptosis in endothelial cells and ultimately contributes to microvascular dysfunction in patients with diabetes mellitus (DM). Previous research reported that the expression of integrins as well as their ligands was elevated in the diseased v...

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Bibliographic Details
Main Authors: Xuze Lin, Sizhuang Huang, Side Gao, Jinxing Liu, Jiong Tang, Mengyue Yu, Rongman Jia, Xiuyuan Hao
Format: Article
Language:English
Published: Wolters Kluwer 2024-03-01
Series:Chinese Medical Journal
Online Access:http://journals.lww.com/10.1097/CM9.0000000000002769