B Cell Subsets and Immune Checkpoint Expression in Patients with Chronic Lymphocytic Leukemia

Chronic lymphocytic leukemia (CLL) is characterized by dysfunctional B cells. Immune checkpoint molecules such as cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) and programmed death-1 (PD-1) are upregulated in patients with CLL and may correlate with prognostic markers such as beta-2 microglob...

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Bibliographic Details
Main Authors: Aviwe Ntsethe, Zekhethelo Alondwe Mkhwanazi, Phiwayinkosi Vusi Dludla, Bongani Brian Nkambule
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:Current Issues in Molecular Biology
Subjects:
Online Access:https://www.mdpi.com/1467-3045/46/3/112