An iron-chelating sulfonamide identified from Drosophila-based screening for antipathogenic discovery
We exploited bacterial infection assays using the fruit fly Drosophila melanogaster to identify anti-infective compounds that abrogate the pathological consequences in the infected hosts. Here, we demonstrated that a pyridine-3-N-sulfonylpiperidine derivative (4a) protects Drosophila from the acute...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Taylor & Francis Group
2022-12-01
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Series: | Virulence |
Subjects: | |
Online Access: | https://www.tandfonline.com/doi/10.1080/21505594.2022.2069325 |