An iron-chelating sulfonamide identified from Drosophila-based screening for antipathogenic discovery

We exploited bacterial infection assays using the fruit fly Drosophila melanogaster to identify anti-infective compounds that abrogate the pathological consequences in the infected hosts. Here, we demonstrated that a pyridine-3-N-sulfonylpiperidine derivative (4a) protects Drosophila from the acute...

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Bibliographic Details
Main Authors: Yeon-Ji Yoo, In-Young Chung, Shivakumar S. Jalde, Hyun-Kyung Choi, You-Hee Cho
Format: Article
Language:English
Published: Taylor & Francis Group 2022-12-01
Series:Virulence
Subjects:
Online Access:https://www.tandfonline.com/doi/10.1080/21505594.2022.2069325

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