The novel long non-coding RNA LATS2-AS1-001 inhibits gastric cancer progression by regulating the LATS2/YAP1 signaling pathway via binding to EZH2

The novel long non-coding RNA LATS2-AS1-001 inhibits gastric cancer progression by regulating the LATS2/YAP1 signaling pathway via binding to EZH2

Abstract Background To explore the expression pattern and role of the novel long non-coding RNA LATS2 antisense transcript 1 (LATS2-AS1-001) in gastric cancer (GC). Methods qRT-PCR was applied to evaluate LATS2-AS1-001 expression and correlation with LATS2 in GC. In vitro experiments were performed...

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Bibliographic Details
Main Authors: Dan Sun, Ying Wang, Huan Wang, Yan Xin
Format: Article
Language:English
Published: BMC 2020-05-01
Series:Cancer Cell International
Subjects:
Long non-coding RNA
Large tumor suppressor 2/LATS2
Yes-associated protein 1/YAP1
Enhancer of zeste homolog 2/EZH2
Gastric cancer
Online Access:http://link.springer.com/article/10.1186/s12935-020-01285-w

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http://link.springer.com/article/10.1186/s12935-020-01285-w

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