Therapeutic Drug Monitoring of Tacrolimus-Personalized Therapy in Heart Transplantation: New Strategies and Preliminary Results in Endomyocardial Biopsies

Therapeutic Drug Monitoring of Tacrolimus-Personalized Therapy in Heart Transplantation: New Strategies and Preliminary Results in Endomyocardial Biopsies

Tacrolimus (TAC) is an immunosuppressant drug approved both in the US and in the EU, widely used for the prophylaxis of organ rejection after transplantation. This is a critical dose drug: low levels in whole blood can lead to low exposure and a high risk of acute rejection, whereas overexposure put...

Full description

Bibliographic Details
Main Authors: Simona De Gregori, Annalisa De Silvestri, Barbara Cattadori, Andrea Rapagnani, Riccardo Albertini, Elisa Novello, Monica Concardi, Eloisa Arbustini, Carlo Pellegrini
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Pharmaceutics
Subjects:
heart transplantation
acute rejection
therapeutic drug monitoring
tacrolimus
endomyocardial biopsies
Online Access:https://www.mdpi.com/1999-4923/14/6/1247

Internet

https://www.mdpi.com/1999-4923/14/6/1247

Similar Items