Characterisation of Plasmodium vivax lactate dehydrogenase dynamics in P. vivax infections

Abstract Plasmodium vivax lactate dehydrogenase (PvLDH) is an essential enzyme in the glycolytic pathway of P. vivax. It is widely used as a diagnostic biomarker and a measure of total-body parasite biomass in vivax malaria. However, the dynamics of PvLDH remains poorly understood. Here, we develope...

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Bibliographic Details
Main Authors: Pengxing Cao, Steven Kho, Matthew J. Grigg, Bridget E. Barber, Kim A. Piera, Timothy William, Jeanne R. Poespoprodjo, Ihn Kyung Jang, Julie A. Simpson, James M. McCaw, Nicholas M. Anstey, James S. McCarthy, Sumudu Britton
Format: Article
Language:English
Published: Nature Portfolio 2024-03-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-024-05956-6