Dimethylamine as the key intermediate generated in situ from dimethylformamide (DMF) for the synthesis of thioamides

An improved and efficient method for the synthesis of thioamides is presented. For this transformation, dimethylamine as the key intermediate is generated in situ from dimethylformamide (DMF). All the tested substrates produced the desired products with excellent isolated yields.

Bibliographic Details
Main Authors: Weibing Liu, Cui Chen, Hailing Liu
Format: Article
Language:English
Published: Beilstein-Institut 2015-09-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
Online Access:https://doi.org/10.3762/bjoc.11.187