Dimethylamine as the key intermediate generated in situ from dimethylformamide (DMF) for the synthesis of thioamides
An improved and efficient method for the synthesis of thioamides is presented. For this transformation, dimethylamine as the key intermediate is generated in situ from dimethylformamide (DMF). All the tested substrates produced the desired products with excellent isolated yields.
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Beilstein-Institut
2015-09-01
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| Series: | Beilstein Journal of Organic Chemistry |
| Subjects: | |
| Online Access: | https://doi.org/10.3762/bjoc.11.187 |
| _version_ | 1831539003084505088 |
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| author | Weibing Liu Cui Chen Hailing Liu |
| author_facet | Weibing Liu Cui Chen Hailing Liu |
| author_sort | Weibing Liu |
| collection | DOAJ |
| description | An improved and efficient method for the synthesis of thioamides is presented. For this transformation, dimethylamine as the key intermediate is generated in situ from dimethylformamide (DMF). All the tested substrates produced the desired products with excellent isolated yields. |
| first_indexed | 2024-12-16T23:33:52Z |
| format | Article |
| id | doaj.art-d48be1423c7e4d849f5bd8e595063380 |
| institution | Directory Open Access Journal |
| issn | 1860-5397 |
| language | English |
| last_indexed | 2024-12-16T23:33:52Z |
| publishDate | 2015-09-01 |
| publisher | Beilstein-Institut |
| record_format | Article |
| series | Beilstein Journal of Organic Chemistry |
| spelling | doaj.art-d48be1423c7e4d849f5bd8e5950633802022-12-21T22:11:48ZengBeilstein-InstitutBeilstein Journal of Organic Chemistry1860-53972015-09-011111721172610.3762/bjoc.11.1871860-5397-11-187Dimethylamine as the key intermediate generated in situ from dimethylformamide (DMF) for the synthesis of thioamidesWeibing Liu0Cui Chen1Hailing Liu2College of Chemical Engineering, Guangdong University of Petrochemical Technology, 2 Guandu Road, Maoming 525000, P. R. China, Fax: +86-668-2923575; Tel: +86-668-2923956College of Chemical Engineering, Guangdong University of Petrochemical Technology, 2 Guandu Road, Maoming 525000, P. R. China, Fax: +86-668-2923575; Tel: +86-668-2923956College Analytical and Testing Centre, Beijing Normal University, No. 19, Xinjiekouwai St., Haidian District, Beijing 100875, P. R. China; Tel: +86-15010928428An improved and efficient method for the synthesis of thioamides is presented. For this transformation, dimethylamine as the key intermediate is generated in situ from dimethylformamide (DMF). All the tested substrates produced the desired products with excellent isolated yields.https://doi.org/10.3762/bjoc.11.187aldehydesdimethylformamide (DMF)elemental sulfurketonesthioamides |
| spellingShingle | Weibing Liu Cui Chen Hailing Liu Dimethylamine as the key intermediate generated in situ from dimethylformamide (DMF) for the synthesis of thioamides Beilstein Journal of Organic Chemistry aldehydes dimethylformamide (DMF) elemental sulfur ketones thioamides |
| title | Dimethylamine as the key intermediate generated in situ from dimethylformamide (DMF) for the synthesis of thioamides |
| title_full | Dimethylamine as the key intermediate generated in situ from dimethylformamide (DMF) for the synthesis of thioamides |
| title_fullStr | Dimethylamine as the key intermediate generated in situ from dimethylformamide (DMF) for the synthesis of thioamides |
| title_full_unstemmed | Dimethylamine as the key intermediate generated in situ from dimethylformamide (DMF) for the synthesis of thioamides |
| title_short | Dimethylamine as the key intermediate generated in situ from dimethylformamide (DMF) for the synthesis of thioamides |
| title_sort | dimethylamine as the key intermediate generated in situ from dimethylformamide dmf for the synthesis of thioamides |
| topic | aldehydes dimethylformamide (DMF) elemental sulfur ketones thioamides |
| url | https://doi.org/10.3762/bjoc.11.187 |
| work_keys_str_mv | AT weibingliu dimethylamineasthekeyintermediategeneratedinsitufromdimethylformamidedmfforthesynthesisofthioamides AT cuichen dimethylamineasthekeyintermediategeneratedinsitufromdimethylformamidedmfforthesynthesisofthioamides AT hailingliu dimethylamineasthekeyintermediategeneratedinsitufromdimethylformamidedmfforthesynthesisofthioamides |