Hippocampal functional connectivity across age in an App knock-in mouse model of Alzheimer's disease

Hippocampal functional connectivity across age in an App knock-in mouse model of Alzheimer's disease

IntroductionAlzheimer's disease (AD) is a progressive neurodegenerative disease. The early processes of AD, however, are not fully understood and likely begin years before symptoms manifest. Importantly, disruption of the default mode network, including the hippocampus, has been implicated in A...

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Bibliographic Details
Main Authors: Zachery D. Morrissey, Jin Gao, Liang Zhan, Weiguo Li, Igor Fortel, Takaomi Saido, Takashi Saito, Arnold Bakker, Scott Mackin, Olusola Ajilore, Orly Lazarov, Alex D. Leow
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Aging Neuroscience
Subjects:
Alzheimer's disease
functional connectome
interhemispheric
resting-state functional magnetic resonance imaging (rs-fMRI)
AppNL-G-F/NL-G-F
hippocampus
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2022.1085989/full

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https://www.frontiersin.org/articles/10.3389/fnagi.2022.1085989/full

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