Skp1 Independent Function of Cdc53/Cul1 in F-box Protein Homeostasis.

Abundance of substrate receptor subunits of Cullin-RING ubiquitin ligases (CRLs) is tightly controlled to maintain the full repertoire of CRLs. Unbalanced levels can lead to sequestration of CRL core components by a few overabundant substrate receptors. Numerous diseases, including cancer, have been...

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Bibliografski detalji
Glavni autori: Radhika Mathur, James L Yen, Peter Kaiser
Format: Članak
Jezik:English
Izdano: Public Library of Science (PLoS) 2015-12-01
Serija:PLoS Genetics
Online pristup:https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1005727&type=printable