Skp1 Independent Function of Cdc53/Cul1 in F-box Protein Homeostasis.
Abundance of substrate receptor subunits of Cullin-RING ubiquitin ligases (CRLs) is tightly controlled to maintain the full repertoire of CRLs. Unbalanced levels can lead to sequestration of CRL core components by a few overabundant substrate receptors. Numerous diseases, including cancer, have been...
Glavni autori: | , , |
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Format: | Članak |
Jezik: | English |
Izdano: |
Public Library of Science (PLoS)
2015-12-01
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Serija: | PLoS Genetics |
Online pristup: | https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1005727&type=printable |