Spatial tumour gene signature discriminates neoplastic from non-neoplastic compartments in colon cancer: unravelling predictive biomarkers for relapse

Spatial tumour gene signature discriminates neoplastic from non-neoplastic compartments in colon cancer: unravelling predictive biomarkers for relapse

Abstract Background Opting for or against the administration of adjuvant chemotherapy in therapeutic management of stage II colon cancer remains challenging. Several studies report few survival benefits for patients treated with adjuvant therapy and additionally revealing potential side effects of o...

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Bibliographic Details
Main Authors: Katja Sallinger, Michael Gruber, Christin-Therese Müller, Lilli Bonstingl, Elisabeth Pritz, Karin Pankratz, Armin Gerger, Maria Anna Smolle, Ariane Aigelsreiter, Olga Surova, Jessica Svedlund, Mats Nilsson, Thomas Kroneis, Amin El-Heliebi
Format: Article
Language:English
Published: BMC 2023-08-01
Series:Journal of Translational Medicine
Subjects:
In situ sequencing
Spatial transcriptomics
colon cancer
Predictive biomarker
Tumour compartment
Tumour gene signature
Online Access:https://doi.org/10.1186/s12967-023-04384-0

Internet

https://doi.org/10.1186/s12967-023-04384-0

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