Mitochondrial Regulation of the Hypoxia-Inducible Factor in the Development of Pulmonary Hypertension

Mitochondrial Regulation of the Hypoxia-Inducible Factor in the Development of Pulmonary Hypertension

Pulmonary hypertension (PH) is a severe progressive lung disorder characterized by pulmonary vasoconstriction and vascular remodeling, culminating in right-sided heart failure and increased mortality. Data from animal models and human subjects demonstrated that hypoxia-inducible factor (HIF)-related...

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Bibliographic Details
Main Authors: Esraa M. Zeidan, Mohammad Akbar Hossain, Mahmoud El-Daly, Mohammed A. S. Abourehab, Mohamed M. A. Khalifa, Ashraf Taye
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Journal of Clinical Medicine
Subjects:
HIF
hypoxia-inducible factor
mitochondria
pulmonary hypertension pathogenesis
Online Access:https://www.mdpi.com/2077-0383/11/17/5219

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https://www.mdpi.com/2077-0383/11/17/5219

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