Newer-Generation EGFR Inhibitors in Lung Cancer: How Are They Best Used?

The FLAURA trial established osimertinib, a third-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI), as a viable first-line therapy in non-small cell lung cancer (NSCLC) with sensitizing EGFR mutations, namely exon 19 deletion and L858R. In this phase 3 randomized, c...

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Bibliographic Details
Main Authors: Tri Le, David E. Gerber
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:Cancers
Subjects:
Online Access:http://www.mdpi.com/2072-6694/11/3/366