The S68G polymorphism is a compensatory mutation associated with the drug resistance mutation K65R in CRF01_AE strains

Abstract Background The rate of S68G mutation in human immunodeficiency virus type 1 (HIV-1) reverse transcriptase has increased and is closely related to the K65R mutation among CRF01_AE-infected patients who failed treatment. We aimed to explore the temporal association of S68G and K65R mutations...

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Bibliographic Details
Main Authors: Shengjia Li, Jinming Ouyang, Bin Zhao, Minghui An, Lin Wang, Haibo Ding, Min Zhang, Xiaoxu Han
Format: Article
Language:English
Published: BMC 2020-02-01
Series:BMC Infectious Diseases
Subjects:
Online Access:https://doi.org/10.1186/s12879-020-4836-z