Over-expression of hsa_circ_0088214 suppresses tumor progression by inhibiting Akt signaling pathway in osteosarcoma

Abstract Background To explore the effect of has_circ_0088214 in osteosarcoma cells and corresponding mechanisms. Methods Osteosarcoma cell line MG63 and U2OS were selected in this study. Wound-healing and matrigel transwell assays were performed to detect migration and invasion capacities. CCK-8 as...

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Bibliographic Details
Main Authors: Zhiwei Hao, Yiqun Yang, Daxia Xu, Hongyong Feng, Kunpeng Li, Changbin Ji, Man Li, Honglei Zhang
Format: Article
Language:English
Published: BMC 2023-05-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
Online Access:https://doi.org/10.1186/s13018-023-03873-8