Phosphatidylserine exposure by Toxoplasma gondii is fundamental to balance the immune response granting survival of the parasite and of the host.

Phosphatidylserine exposure by Toxoplasma gondii is fundamental to balance the immune response granting survival of the parasite and of the host.

Phosphatidylserine (PS) exposure on the cell surface indicates apoptosis, but has also been related to evasion mechanisms of parasites, a concept known as apoptotic mimicry. Toxoplasma gondii mimics apoptotic cells by exposing PS, inducing secretion of TGF-beta1 by infected activated macrophages lea...

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Bibliographic Details
Main Authors: Thiago Alves Teixeira dos Santos, Juliana de Araújo Portes, João Claudio Damasceno-Sá, Lucio Ayres Caldas, Wanderley de Souza, Renato Augusto Damatta, Sergio Henrique Seabra
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3226563?pdf=render

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http://europepmc.org/articles/PMC3226563?pdf=render

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