Development of a Sustained Release Nano-In-Gel Delivery System for the Chemotactic and Angiogenic Growth Factor Stromal-Derived Factor 1α

Development of a Sustained Release Nano-In-Gel Delivery System for the Chemotactic and Angiogenic Growth Factor Stromal-Derived Factor 1α

Stromal-Derived Factor 1α (SDF) is an angiogenic, chemotactic protein with significant potential for applications in a range of clinical areas, including wound healing, myocardial infarction and orthopaedic regenerative approaches. The 26-min in vivo half-life of SDF, however, has limited its clinic...

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Bibliographic Details
Main Authors: Joanne O’Dwyer, Megan Cullen, Sarinj Fattah, Robert Murphy, Smiljana Stefanovic, Lenka Kovarova, Martin Pravda, Vladimir Velebny, Andreas Heise, Garry P. Duffy, Sally Ann Cryan
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Pharmaceutics
Subjects:
angiogenesis
stromal-derived factor
sustained release
nanoparticle
hydrogel
chemotaxis
Online Access:https://www.mdpi.com/1999-4923/12/6/513

Internet

https://www.mdpi.com/1999-4923/12/6/513

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