Osteoclast-mediated resorption primes the skeleton for successful integration during axolotl limb regeneration

Osteoclast-mediated resorption primes the skeleton for successful integration during axolotl limb regeneration

Early events during axolotl limb regeneration include an immune response and the formation of a wound epithelium. These events are linked to a clearance of damaged tissue prior to blastema formation and regeneration of the missing structures. Here, we report the resorption of calcified skeletal tiss...

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Bibliographic Details
Main Authors: Camilo Riquelme-Guzmán, Stephanie L Tsai, Karen Carreon Paz, Congtin Nguyen, David Oriola, Maritta Schuez, Jan Brugués, Joshua D Currie, Tatiana Sandoval-Guzmán
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-10-01
Series:eLife
Subjects:
axolotl
regeneration
skeleton
osteoclasts
integration
Online Access:https://elifesciences.org/articles/79966

Internet

https://elifesciences.org/articles/79966

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