Essential Transcription Factors and Functional Roles of Follicular Helper T Cells in Human Autoimmune Diseases

Essential Transcription Factors and Functional Roles of Follicular Helper T Cells in Human Autoimmune Diseases

Follicular helper T (TFH) cells are a subset of effector CD4+ T cells that support the differentiation of antigen-specific B cells in the germinal center. TFH cells are distinct from other established CD4+ T cell subsets and possess a list of transcription factors, including BCL6, IRF4, c-Maf, Batf,...

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Bibliographic Details
Main Authors: Sara Iranparast, Farhad Seif, Sanaz Tayebi, Farhad Abolnezhadian, Moosa Sharifat, Alireza Fazaeli, Neda Roshanravan, Azam Samei, Sholeh Khajoei
Format: Article
Language:English
Published: Shiraz University of Medical Sciences 2022-06-01
Series:Iranian Journal of Immunology
Subjects:
autoimmune diseases
chemokine
follicular helper t cell
germinal center
interleukin
transcription factor
Online Access:https://iji.sums.ac.ir/article_48510_df4288ae680efd68620ac4e1208e8b0e.pdf

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https://iji.sums.ac.ir/article_48510_df4288ae680efd68620ac4e1208e8b0e.pdf

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