Clopidogrel, an ADP-P2Y12 Receptor Antagonist, Can Prevent Severe Postoperative Pain: A Retrospective Chart Review

Clopidogrel, an ADP-P2Y12 Receptor Antagonist, Can Prevent Severe Postoperative Pain: A Retrospective Chart Review

The purinergic P2Y12 receptor regulates microglial activation, resulting in persistence and aggravation of pain in neuropathic and nociceptive pain models. We conducted a retrospective chart review to explore the analgesic potency of the P2Y12 receptor-specific antagonist, clopidogrel, for clinical...

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Bibliographic Details
Main Authors: Rikuhei Tsuchida, Masahiko Sumitani, Hiroaki Abe, Masae Ando, Kosuke Saita, Kohshi Hattori, Kazuhito Mietani, Reo Inoue, Kanji Uchida
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Life
Subjects:
ATP receptor
P2Y12 receptor
clopidogrel
postoperative pain
central sensitisation
Online Access:https://www.mdpi.com/2075-1729/10/6/92

Internet

https://www.mdpi.com/2075-1729/10/6/92

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