Sanguinarine, identified as a natural alkaloid LSD1 inhibitor, suppresses lung cancer cell growth and migration

Sanguinarine, identified as a natural alkaloid LSD1 inhibitor, suppresses lung cancer cell growth and migration

Objective(s): Lysine-specific demethylase1 (LSD1), an important class of histone demethylases, plays a crucial role in regulation of mammalian biology. The up-regulated LSD1 expression was frequently associated with progress and oncogenesis of multiple human cancers, including non-small cell lung ca...

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Bibliographic Details
Main Authors: Ting-ting Qin, Zhong-hua Li, Li-xin Li, Kun Du, Ji-ge Yang, Zhenqiang Zhang, Xiang-xiang Wu, Jinlian Ma
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2022-06-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
antiproliferation
lsd1 inhibitor
migration
nsclc
sanguinarine
Online Access:https://ijbms.mums.ac.ir/article_20354_42324ceffe52bb6e7f88831fa8d037fe.pdf

Internet

https://ijbms.mums.ac.ir/article_20354_42324ceffe52bb6e7f88831fa8d037fe.pdf

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