Sanguinarine, identified as a natural alkaloid LSD1 inhibitor, suppresses lung cancer cell growth and migration
Objective(s): Lysine-specific demethylase1 (LSD1), an important class of histone demethylases, plays a crucial role in regulation of mammalian biology. The up-regulated LSD1 expression was frequently associated with progress and oncogenesis of multiple human cancers, including non-small cell lung ca...
Main Authors: | Ting-ting Qin, Zhong-hua Li, Li-xin Li, Kun Du, Ji-ge Yang, Zhenqiang Zhang, Xiang-xiang Wu, Jinlian Ma |
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Format: | Article |
Language: | English |
Published: |
Mashhad University of Medical Sciences
2022-06-01
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Series: | Iranian Journal of Basic Medical Sciences |
Subjects: | |
Online Access: | https://ijbms.mums.ac.ir/article_20354_42324ceffe52bb6e7f88831fa8d037fe.pdf |
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