Preliminary report of a novel formulation of clinical-grade, fully matured, tumor-associated peptide-loaded dendritic cells for cancer immunotherapy

Preliminary report of a novel formulation of clinical-grade, fully matured, tumor-associated peptide-loaded dendritic cells for cancer immunotherapy

Abstract Background We developed and clinically test a new method to manufacture mature dendritic cells for autologous cell therapy of solid and hematological malignancies. Methods Peripheral blood monocytes are matured into dendritic cells with GM-CSF/IL-4 mixture, and then activated through IL1b,...

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Bibliographic Details
Main Authors: Leonardo Mirandola, Maurizio Chiriva-Internati, Robert Bresalier, Francesco M. Marincola, Jose A. Figueroa, Scott Dahlbeck
Format: Article
Language:English
Published: BMC 2019-11-01
Series:Translational Medicine Communications
Subjects:
Immuno-oncology
Cancer vaccines
Cancer targets
Online Access:http://link.springer.com/article/10.1186/s41231-019-0049-0

Internet

http://link.springer.com/article/10.1186/s41231-019-0049-0

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