Quantitative analysis of in-vivo microbubble distribution in the human brain

Abstract Microbubbles (MB) are widely used as contrast agents to perform contrast-enhanced ultrasound (CEUS) imaging and as acoustic amplifiers of mechanical bioeffects incited by therapeutic-level ultrasound. The distribution of MBs in the brain is not yet fully understood, thereby limiting intra-o...

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Bibliographic Details
Main Authors: Francesco Prada, Antonio G. Gennari, Ian M. Linville, Michael E. Mutersbaugh, Zhihang Chen, Natasha Sheybani, Francesco DiMeco, Frederic Padilla, John A. Hossack
Format: Article
Language:English
Published: Nature Portfolio 2021-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-91252-w