Cochlear progenitor number is controlled through mesenchymal FGF receptor signaling

The sensory and supporting cells (SCs) of the organ of Corti are derived from a limited number of progenitors. The mechanisms that regulate the number of sensory progenitors are not known. Here, we show that Fibroblast Growth Factors (FGF) 9 and 20, which are expressed in the non-sensory (Fgf9) and...

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Bibliographic Details
Main Authors: Sung-Ho Huh, Mark E Warchol, David M Ornitz
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2015-04-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/05921