Targeting inhibition of prognosis-related lipid metabolism genes including CYP19A1 enhances immunotherapeutic response in colon cancer

Targeting inhibition of prognosis-related lipid metabolism genes including CYP19A1 enhances immunotherapeutic response in colon cancer

Abstract Background Lipid metabolic reprogramming in colon cancer shows a potential impact on tumor immune microenvironment and is associated with response to immunotherapy. Therefore, this study aimed to develop a lipid metabolism-related prognostic risk score (LMrisk) to provide new biomarkers and...

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Bibliographic Details
Main Authors: Lilong Liu, Min Mo, Xuehan Chen, Dongchen Chao, Yufan Zhang, Xuewei Chen, Yang Wang, Nan Zhang, Nan He, Xi Yuan, Honglei Chen, Jing Yang
Format: Article
Language:English
Published: BMC 2023-04-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Lipid metabolism
CYP19A1
Tumor immune microenvironment
Immunotherapeutic response
Colon cancer
Online Access:https://doi.org/10.1186/s13046-023-02647-8

Internet

https://doi.org/10.1186/s13046-023-02647-8

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