p14ARF induces the relocation of HDM2 and p53 to extranucleolar sites that are targeted by PML bodies and proteasomes
<p>Abstract</p> <p>Background</p> <p>p14ARF is a protein product of the alternative reading frame of the human INK4a locus. It functions as a tumor suppressor protein. p14ARF suppresses growth through p53-dependent and p53-independent pathways.</p> <p>Result...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2003-03-01
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Series: | Molecular Cancer |
Online Access: | http://www.molecular-cancer.com/content/2/1/18 |