Targeting Common Inflammatory Mediators in Experimental Severe Asthma and Acute Lung Injury

Targeting Common Inflammatory Mediators in Experimental Severe Asthma and Acute Lung Injury

Neutrophils, known to be mobilized and activated in high amounts through Il-17 stimulation, are a key factor for clinical manifestation and imbalance of redox systems favoring a dominant oxidative state in both severe asthma and acute lung injury (f). The aim of this study was to evaluate in mice, t...

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Bibliographic Details
Main Authors: Andrei Gheorghe Vicovan, Diana Cezarina Petrescu, Aurelia Cretu, Cristina Mihaela Ghiciuc, Daniela Constantinescu, Elena Iftimi, Georgiana Strugariu, Codrina Mihaela Ancuta, Cezar-Cătălin Caratașu, Carmen Solcan, Celina Silvia Stafie
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:Pharmaceuticals
Subjects:
Secukinumab
asthma
acute lung injury
Lipopolysaccharide
Interleukin 17
mice
Online Access:https://www.mdpi.com/1424-8247/17/3/338

Internet

https://www.mdpi.com/1424-8247/17/3/338

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