Integrated systems modeling of severe asthma: Exploration of IL‐33/ST2 antagonism

Abstract Asthma is a complex, heterogeneous disease with a high unmet medical need, despite therapies targeting a multitude of pathways. The ability to quantitatively integrate preclinical and clinical data on these pathways could aid in the development and testing of novel targets and therapeutics....

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Bibliographic Details
Main Authors: Kapil Gadkar, Justin Feigelman, Siddharth Sukumaran, Manoj C. Rodrigo, Tracy Staton, Fang Cai, Rebecca N. Bauer, David F. Choy, Cynthia L. Stokes, Heleen Scheerens, Saroja Ramanujan
Format: Article
Language:English
Published: Wiley 2022-09-01
Series:CPT: Pharmacometrics & Systems Pharmacology
Online Access:https://doi.org/10.1002/psp4.12842