In-vitro generation of follicle-like structures from human germ cell-like cells derived from theca stem cell combined with ovarian somatic cells

In-vitro generation of follicle-like structures from human germ cell-like cells derived from theca stem cell combined with ovarian somatic cells

Abstract Background The objective of this study was to induce the differentiation of human theca stem cells (hTSCs) into germ cell-like cells (hGCLCs) and assess their developmental progression following in vitro 3D culture with ovarian somatic cells within the follicle-like structures. To achieve t...

Full description

Bibliographic Details
Main Authors: Seyedeh Nasim Mirbahari, Christiani A. Amorim, Fatemeh Hassani, Mehdi Totonchi, Mahnaz Haddadi, Mojtaba Rezazadeh valojerdi, Azam Dalman
Format: Article
Language:English
Published: BMC 2024-01-01
Series:Journal of Ovarian Research
Subjects:
Human theca stem cells
Germ cell-like cells
Primordial follicle-like structure
In vitro development
Online Access:https://doi.org/10.1186/s13048-023-01315-x

Internet

https://doi.org/10.1186/s13048-023-01315-x

Similar Items