A nanobody recognizes a unique conserved epitope and potently neutralizes SARS-CoV-2 omicron variants

Summary: The severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) Omicron variant sub-lineages spread rapidly worldwide, mostly due to their immune-evasive properties. This has put a significant part of the population at risk for severe disease and underscores the need for effective anti-SARS...

Full description

Bibliographic Details
Main Authors: Naphak Modhiran, Simon Malte Lauer, Alberto A. Amarilla, Peter Hewins, Sara Irene Lopes van den Broek, Yu Shang Low, Nazia Thakur, Benjamin Liang, Guillermo Valenzuela Nieto, James Jung, Devina Paramitha, Ariel Isaacs, Julian D.J. Sng, David Song, Jesper Tranekjær Jørgensen, Yorka Cheuquemilla, Jörg Bürger, Ida Vang Andersen, Johanna Himelreichs, Ronald Jara, Ronan MacLoughlin, Zaray Miranda-Chacon, Pedro Chana-Cuevas, Vasko Kramer, Christian Spahn, Thorsten Mielke, Alexander A. Khromykh, Trent Munro, Martina L. Jones, Paul R. Young, Keith Chappell, Dalan Bailey, Andreas Kjaer, Matthias Manfred Herth, Kellie Ann Jurado, David Schwefel, Alejandro Rojas-Fernandez, Daniel Watterson
Format: Article
Language:English
Published: Elsevier 2023-07-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223011628