Review, analysis, and optimization of the CRISPR Streptococcus pyogenes Cas9 system
Despite certain defects hindering its clinical application, the CRISPR (clustered regularly interspaced short palindromic repeats)-associated (Cas) Streptococcus pyogenes Cas9 (spCas9) system is the most studied and the most popular tool for genome editing. The mechanism underlying the action of the...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2021-03-01
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| Series: | Medicine in Drug Discovery |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2590098621000014 |