Alkannin exerts antitumor properties in cutaneous squamous cell carcinoma by inducing apoptosis and shifting the M1/M2 polarization of tumor‐associated macrophages by upregulating PTEN

Alkannin exerts antitumor properties in cutaneous squamous cell carcinoma by inducing apoptosis and shifting the M1/M2 polarization of tumor‐associated macrophages by upregulating PTEN

Abstract Cutaneous squamous cell carcinoma (CSCC) is a common cancer in humans and is the second major type of skin cancer that causes death in humans. In this article, we investigated the effects of alkannin on CSCC progression. We revealed that alkannin curbed CSCC cell viability in a dose‐depende...

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Bibliographic Details
Main Authors: Zhong‐Zhao Zhang, Chang‐Hui Wen, Min Jia, Hong‐Qiang Zhang, Shao‐Qin Sun
Format: Article
Language:English
Published: Wiley 2023-01-01
Series:Kaohsiung Journal of Medical Sciences
Subjects:
alkannin
cutaneous squamous cell carcinoma
M1 polarization
phosphatase and tensin homolog
Online Access:https://doi.org/10.1002/kjm2.12617

Internet

https://doi.org/10.1002/kjm2.12617

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