Drug resistance analysis by next generation sequencing in Leishmania

The use of next generation sequencing has the power to expedite the identification of drug resistance determinants and biomarkers and was applied successfully to drug resistance studies in Leishmania. This allowed the identification of modulation in gene expression, gene dosage alterations, changes...

Full description

Bibliographic Details
Main Authors: Philippe Leprohon, Christopher Fernandez-Prada, Élodie Gazanion, Rubens Monte-Neto, Marc Ouellette
Format: Article
Language:English
Published: Elsevier 2015-04-01
Series:International Journal for Parasitology: Drugs and Drug Resistance
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211320714000281