The Human RNA Helicase DDX21 Presents a Dimerization Interface Necessary for Helicase Activity

The Human RNA Helicase DDX21 Presents a Dimerization Interface Necessary for Helicase Activity

Summary: Members of the DEAD-box helicase family are involved in all fundamental processes of RNA metabolism, and as such, their malfunction is associated with various diseases. Currently, whether and how oligomerization impacts their biochemical and biological functions is not well understood. In t...

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Bibliographic Details
Main Authors: Maria J. Marcaida, Annamaria Kauzlaric, Alice Duperrex, Jenny Sülzle, Martin C. Moncrieffe, Damilola Adebajo, Suliana Manley, Didier Trono, Matteo Dal Peraro
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:iScience
Subjects:
Molecular Modelling
Biological Sciences
Molecular Biology
Structural Biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004220310087

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http://www.sciencedirect.com/science/article/pii/S2589004220310087

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