Low Expression of SLC7A11 Confers Drug Resistance and Worse Survival in Ovarian Cancer via Inhibition of Cell Autophagy as a Competing Endogenous RNA

Low Expression of SLC7A11 Confers Drug Resistance and Worse Survival in Ovarian Cancer via Inhibition of Cell Autophagy as a Competing Endogenous RNA

Drug resistance is the main cause of chemotherapy failure in ovarian cancer (OC), and identifying potential druggable targets of autophagy is a novel and promising approach to overcoming drug resistance. In this study, 131 genes associated with autophagy were identified from three autophagy-related...

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Bibliographic Details
Main Authors: Yao Ke, Xiaoying Chen, Yuting Su, Cuilan Chen, Shunmei Lei, Lianping Xia, Dan Wei, Han Zhang, Caihua Dong, Xia Liu, Fuqiang Yin
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Oncology
Subjects:
SLC7A11
ovarian cancer
drug resistance
ceRNA
autophagy
prognosis
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.744940/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2021.744940/full

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