Transcriptome and proteome profiling reveals complex adaptations of Candida parapsilosis cells assimilating hydroxyaromatic carbon sources.

Many fungal species utilize hydroxyderivatives of benzene and benzoic acid as carbon sources. The yeast Candida parapsilosis metabolizes these compounds via the 3-oxoadipate and gentisate pathways, whose components are encoded by two metabolic gene clusters. In this study, we determine the chromosom...

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Main Authors: Andrea Cillingová, Renáta Tóth, Anna Mojáková, Igor Zeman, Romana Vrzoňová, Barbara Siváková, Peter Baráth, Martina Neboháčová, Zuzana Klepcová, Filip Brázdovič, Hana Lichancová, Viktória Hodorová, Broňa Brejová, Tomáš Vinař, Sofia Mutalová, Veronika Vozáriková, Giacomo Mutti, Ľubomír Tomáška, Atilla Gácser, Toni Gabaldón, Jozef Nosek
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-03-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1009815