In Vitro Characterization of the Innate Immune Pathways Engaged by Live and Inactivated Tick-Borne Encephalitis Virus

In Vitro Characterization of the Innate Immune Pathways Engaged by Live and Inactivated Tick-Borne Encephalitis Virus

Tick-borne encephalitis virus (TBEV) infection can lead to inflammation of the central nervous system. The disease can be effectively prevented by whole inactivated virus vaccines. Here, we investigated the innate immune profile induced in vitro by the antigen component of the vaccines, inactivated...

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Bibliographic Details
Main Authors: Aurora Signorazzi, Jeroen L. A. Pennings, Marilena P. Etna, Malou Noya, Eliana M. Coccia, Anke Huckriede
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Vaccines
Subjects:
tick-borne encephalitis virus
TBE vaccine
peripheral blood mononuclear cells
RNA sequencing
interferon
RIG-I
Online Access:https://www.mdpi.com/2076-393X/9/6/664

Internet

https://www.mdpi.com/2076-393X/9/6/664

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