Protocol to evaluate the antiviral effect of FDA-approved drugs against dengue virus in Huh7 cells and AG129 mice

Protocol to evaluate the antiviral effect of FDA-approved drugs against dengue virus in Huh7 cells and AG129 mice

Summary: Finding an effective therapy against diseases caused by flaviviruses remains a challenge. Here, we present a protocol to test Food and Drug Administration-approved drugs that inhibit host nuclear protein import, promoting a reduction of dengue infection. We describe steps for analyzing the...

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Bibliographic Details
Main Authors: Selvin Noé Palacios-Rápalo, Jonathan Hernández-Castillo, Carlos Daniel Cordero-Rivera, Magda Lizbeth Benítez-Vega, Luis Adrián De Jesús-González, José Manuel Reyes-Ruiz, Carlos Noe Farfan-Morales, Juan Fidel Osuna-Ramos, Arely M. Gonzalez-Gonzalez, Raymundo Cruz, Rosa María del Ángel
Format: Article
Language:English
Published: Elsevier 2024-06-01
Series:STAR Protocols
Subjects:
Cell Biology
Flow Cytometry
Health Sciences
Microbiology
Microscopy
Model Organisms
Online Access:http://www.sciencedirect.com/science/article/pii/S2666166724001576

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http://www.sciencedirect.com/science/article/pii/S2666166724001576

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