Mutation saturation for fitness effects at human CpG sites

Whole exome sequences have now been collected for millions of humans, with the related goals of identifying pathogenic mutations in patients and establishing reference repositories of data from unaffected individuals. As a result, we are approaching an important limit, in which datasets are large en...

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Detalles Bibliográficos
Main Authors: Ipsita Agarwal, Molly Przeworski
Formato: Artigo
Idioma:English
Publicado: eLife Sciences Publications Ltd 2021-11-01
Series:eLife
Subjects:
Acceso en liña:https://elifesciences.org/articles/71513