Benzimidazole carbamate induces cytotoxicity in breast cancer cells via two distinct cell death mechanisms

Abstract Metastatic breast cancer (mBC) is responsible for >90% of breast cancer-related deaths. Microtubule-targeting agents (MTAs) are the front-line treatment for mBC. However, the effectiveness of MTAs is frequently limited by the primary or acquired resistance. Furthermore, recurrent mBC der...

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Bibliographic Details
Main Authors: Brendan T. Graff, Chitra Palanivel, Christopher B. Jenkins, Janina Baranowska-Kortylewicz, Ying Yan
Format: Article
Language:English
Published: Nature Publishing Group 2023-05-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-023-01454-6