Insights into the inhibition of type I-F CRISPR-Cas system by a multifunctional anti-CRISPR protein AcrIF24
Phages use anti-CRISPR proteins (Acrs) to counteract the bacterial CRISPR-Cas systems. Here, the authors characterize AcrIF24, which functions as an Aca (Acr-associated) to repress and regulate its own transcription, dimerizes the Csy complex, blocks the hybridization of target DNA, and tethers non-...
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Bibliographic Details
| Main Authors: |
Lingguang Yang,
Laixing Zhang,
Peipei Yin,
Hao Ding,
Yu Xiao,
Jianwei Zeng,
Wenhe Wang,
Huan Zhou,
Qisheng Wang,
Yi Zhang,
Zeliang Chen,
Maojun Yang,
Yue Feng |
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| Format: | Article
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| Language: | English |
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| Published: |
Nature Portfolio
2022-04-01
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| Series: | Nature Communications
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| Online Access: | https://doi.org/10.1038/s41467-022-29581-1
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