Computational identification of Vernonia cinerea-derived phytochemicals as potential inhibitors of nonstructural protein 1 (NSP1) in dengue virus serotype-2

Computational identification of Vernonia cinerea-derived phytochemicals as potential inhibitors of nonstructural protein 1 (NSP1) in dengue virus serotype-2

BackgroundDengue virus (DENV) infection, spread by Aedes aegypti mosquitoes, is a significant public health concern in tropical and subtropical regions. Among the four distinct serotypes of DENV (DENV-1 to DENV-4), DENV-2 is associated with the highest number of fatalities worldwide. However, there...

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Detalhes bibliográficos
Principais autores: Md. Shohel Hossain, Soharth Hasnat, Shilpy Akter, Maria Mulla Mim, Anika Tahcin, Majedul Hoque, Durjoy Sutradhar, Mst. Alifa Akter Keya, Namin Rouf Sium, Sophia Hossain, Runa Masuma, Sakhawat Hossen Rakib, Md. Aminul Islam, Tofazzal Islam, Prosun Bhattacharya, M. Nazmul Hoque
Formato: Artigo
Idioma:English
Publicado em: Frontiers Media S.A. 2024-10-01
coleção:Frontiers in Pharmacology
Assuntos:
DENV-2
NSP1
V. cinerea
molecular screening
molecular dynamics simulation
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fphar.2024.1465827/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2024.1465827/full

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