Molecular characterization of cytidine monophospho-N-acetylneuraminic acid hydroxylase (CMAH) associated with the erythrocyte antigens in dogs

Abstract Background N-glycolylneuraminic acid (Neu5Gc) is synthesized from its precursor N-acetylneuraminic acid (Neu5Ac) by cytidine-5′-monophospho-N acetylneuraminic acid hydroxylase (CMAH), which is encoded by the CMAH gene. Most mammals have both Neu5Gc and Neu5Ac, but humans and ferrets have on...

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Bibliographic Details
Main Authors: Yumiko Uno, Shota Kawakami, Kazuhiko Ochiai, Toshinori Omi
Format: Article
Language:English
Published: BMC 2019-11-01
Series:Canine Genetics and Epidemiology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s40575-019-0076-1