Simulation of Vancomycin Exposure Using Trough and Peak Levels Achieves the Target Area under the Steady-State Concentration–Time Curve in ICU Patients

Simulation of Vancomycin Exposure Using Trough and Peak Levels Achieves the Target Area under the Steady-State Concentration–Time Curve in ICU Patients

The therapeutic drug monitoring (TDM) of vancomycin (VCM) in critically ill patients often results in the estimated area being under the concentration–time curve (AUC) values that deviate from individual observations. In this study, we investigated the factors influencing the achievement of the targ...

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Bibliographic Details
Main Authors: Yuta Ibe, Tomoyuki Ishigo, Satoshi Fujii, Satoshi Takahashi, Masahide Fukudo, Hideki Sato
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Antibiotics
Subjects:
area under the concentration–time curve
critically ill patients
intensive care unit
therapeutic drug monitoring
vancomycin
Online Access:https://www.mdpi.com/2079-6382/12/7/1113

Internet

https://www.mdpi.com/2079-6382/12/7/1113

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