Nitric Oxide Synthase Neurons in the Preoptic Hypothalamus Are NREM and REM Sleep-Active and Lower Body Temperature

Nitric Oxide Synthase Neurons in the Preoptic Hypothalamus Are NREM and REM Sleep-Active and Lower Body Temperature

When mice are exposed to external warmth, nitric oxide synthase (NOS1) neurons in the median and medial preoptic (MnPO/MPO) hypothalamus induce sleep and concomitant body cooling. However, how these neurons regulate baseline sleep and body temperature is unknown. Using calcium photometry, we show th...

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Bibliographic Details
Main Authors: Edward C. Harding, Wei Ba, Reesha Zahir, Xiao Yu, Raquel Yustos, Bryan Hsieh, Leda Lignos, Alexei L. Vyssotski, Florian T. Merkle, Timothy G. Constandinou, Nicholas P. Franks, William Wisden
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Neuroscience
Subjects:
preoptic hypothalamus
nitric oxide
sleep
calcium photometry
body temperature
tetanus-toxin light-chain
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2021.709825/full

Internet

https://www.frontiersin.org/articles/10.3389/fnins.2021.709825/full

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