Covariance-based vs. correlation-based functional connectivity dissociates healthy aging from Alzheimer disease

Covariance-based vs. correlation-based functional connectivity dissociates healthy aging from Alzheimer disease

Prior studies of aging and Alzheimer disease have evaluated resting state functional connectivity (FC) using either seed-based correlation (SBC) or independent component analysis (ICA), with a focus on particular functional systems. SBC and ICA both are insensitive to differences in signal amplitude...

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Bibliographic Details
Main Authors: Jeremy F. Strain, Matthew R. Brier, Aaron Tanenbaum, Brian A. Gordon, John E. McCarthy, Aylin Dincer, Daniel S. Marcus, Jasmeer P. Chhatwal, Neill R. Graff-Radford, Gregory S. Day, Christian la Fougère, Richard J. Perrin, Stephen Salloway, Peter R. Schofield, Igor Yakushev, Takeshi Ikeuchi, Jonathan Vöglein, John C. Morris, Tammie L.S. Benzinger, Randall J. Bateman, Beau M. Ances, Abraham Z. Snyder
Format: Article
Language:English
Published: Elsevier 2022-11-01
Series:NeuroImage
Subjects:
Resting-state functional connectivity
Covariance
Aging
Late onset Alzheimer disease
Autosomal dominant Alzheimer disease
Online Access:http://www.sciencedirect.com/science/article/pii/S1053811922006279

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http://www.sciencedirect.com/science/article/pii/S1053811922006279

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