MiR145-5p inhibits proliferation of PMVECs via PAI-1 in experimental hepatopulmonary syndrome rat pulmonary microvascular hyperplasia

MiR145-5p inhibits proliferation of PMVECs via PAI-1 in experimental hepatopulmonary syndrome rat pulmonary microvascular hyperplasia

Hepatopulmonary syndrome (HPS) is a triad of advanced liver disease, intrapulmonary vasodilatation and arterial hypoxemia. Increasing evidence shows that HPS is associated with pulmonary microvascular hyperplasia. The aim of this work was to investigate the underlying mechanism of miR-145 in regulat...

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Bibliographic Details
Main Authors: Yang Chen, Congwen Yang, Yujie Li, Lin Chen, Yong Yang, Karine Belguise, Xiaobo Wang, Kaizhi Lu, Bin Yi
Format: Article
Language:English
Published: The Company of Biologists 2019-11-01
Series:Biology Open
Subjects:
hepatopulmonary syndrome (hps)
plasminogen activator inhibitor-1 (pai-1)
mir145-5p
pulmonary microvascular endothelial cells (pmvecs)
Online Access:http://bio.biologists.org/content/8/11/bio044800

Internet

http://bio.biologists.org/content/8/11/bio044800

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